Quote:During brain development, neurons have to connect to each other, which they do by extending their long axons to touch one another. Ultimately, these neurons form a circuit between the brain and the target tissue through which chemical and electrical signals are relayed. In this study, researchers investigated neurons that travel up the spinal cord into the brain. "It is very critical that axons are precisely positioned in the spinal cord," Dr. Jaffrey says. "If they are improperly positioned, they will form the wrong connections, which can lead to signals being sent to the wrong target cells in the brain." The way that an axon guides and finds its proper target is through so-called growth cones located at the tips of axons. "These growth cones have the ability to sense the environment, determine where the targets are and navigate toward them. The question has always been—how do they know how to do this? Where do the instructions come from that tell them how to find their proper target?" Dr. Jaffrey says. The team found that RNA molecules embedded in the growth cone are responsible for instructing the axon to move left or right, up or down. These RNAs are translated in growth cones to produce antenna-like proteins that steer the axon like a self-guided missile. "As a circuit is being built, RNAs in the neuron's growth cones are mostly silent. We found that specific RNAs are only read at precise stages in order to produce the right protein needed to steer the axon at the right time. After the protein is produced, we saw that the RNA instruction is degraded and disappears," he says. "If these RNAs do not disappear when they should, the axon does not position itself properly—it may go right instead of left—and the wiring will be incorrect and the circuit may be faulty," Dr. Jaffrey says.Read more at: http://medicalxpress.com/news/2013-06-br...d.html#jCp
it's like it's supposed to be important or sumpin'
though i don't know why
Quote:The human brain is heralded for its staggering complexity and processing capacity: its hundred billion neurons and several hundred trillion synaptic connections can process and exchange prodigious amounts of information over a distributed neural network in the matter of milliseconds.http://theastronomist.fieldofscience.com...brain.html
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