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Scientists figure out how to erase Alzheimer’s damage
04-11-2018, 07:43 AM #1
Richie Incognito
 
Quote:Scientists in California successfully changed a protein associated with Alzheimer’s disease into a more harmless form, allowing them to erase brain cell damage. The breakthrough is important as the research was not conducted on mice but rather human cells.

Researchers from the Gladstone Institutes in San Francisco took stem cells from Alzheimer’s patients who had two copies of the apoE4 gene as well as stem cells from two healthy volunteers who also had a pair of the apoE4 gene, a study published online Tuesday said. They then created neurons, or brain cells, from these stem cells.

Through studying these neurons, the team was able to identify exactly why apoE4 puts individuals at such increased risk for Alzheimer’s disease. For example, having one apoE4 gene more than doubles the chances of developing Alzheimer’s disease, and possessing two copies of the gene increases risk of developing the neurodegenerative brain disease by 12-fold, a statement on the study reported.

Read the rest: rawstory.com

An end to this is an extraordinary development.
04-11-2018, 07:45 AM #2
Octo Mother Superior
Posts:41,655 Threads:1,594 Joined:Feb 2011
That's fantastic news, I hope it leads somewhere!
04-11-2018, 07:52 AM #3
JayRodney ⓐⓛⓘⓔⓝ
Posts:30,350 Threads:1,497 Joined:Feb 2011
This is big, I lost my mom to it several years ago.

wonder.gif

04-11-2018, 12:03 PM #4
Mars Member
Posts:747 Threads:45 Joined:Aug 2013
Sorry to hear that JR, but this was a great find OP. I hope this comes to fruition.
04-11-2018, 12:23 PM #5
Kreeper Griobhtha
Posts:11,169 Threads:770 Joined:Feb 2011
A cure? Nope. It will fail. We can't have big pharma making cures. There is no profit in cures.

What politics from both sides wants to teach us is that things are never complex. If you have your little package and something doesn't fit into that package, You don't know what to make of it so you want to dismiss it or then you will have to do the work of reconsidering your assumptions. - Michael Malice
04-11-2018, 01:05 PM #6
JayRodney ⓐⓛⓘⓔⓝ
Posts:30,350 Threads:1,497 Joined:Feb 2011
bored.gif Yeah... sometimes I get a glimmer of false hope, I really should know better.

wonder.gif

04-11-2018, 02:09 PM #7
Kreeper Griobhtha
Posts:11,169 Threads:770 Joined:Feb 2011
It is bad enough that if anything looks like it might cure something, or even ease symptoms, then they have it made illegal.

What politics from both sides wants to teach us is that things are never complex. If you have your little package and something doesn't fit into that package, You don't know what to make of it so you want to dismiss it or then you will have to do the work of reconsidering your assumptions. - Michael Malice
04-11-2018, 03:27 PM #8
UniqueStranger Art in my heart
Posts:15,873 Threads:483 Joined:Jun 2012
Sorry to hear that JR, I too lost my grandmother that way too, she was near 80 years old though. Anyway, this is impressive news but I wonder how they managed to change the protein into a harmless version...that will take some heavy reading to find out.
04-11-2018, 05:22 PM #9
Meh Member
Posts:1,161 Threads:46 Joined:Apr 2017
This could be a step in the right direction, one of my grandfathers sisters passed from that.
04-11-2018, 08:04 PM #10
Cynicalabsurdance Member
Posts:10,602 Threads:242 Joined:Feb 2011
About damned Time I say


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04-11-2018, 08:28 PM #11
JayRodney ⓐⓛⓘⓔⓝ
Posts:30,350 Threads:1,497 Joined:Feb 2011
Yup, they've been at that a very long time.
Won't hold my breath, but could be a game changer.
Now, if they could get it together on cancer. gaah.gif

wonder.gif

04-11-2018, 09:30 PM #12
Adde All in Moderation
Posts:837 Threads:55 Joined:Apr 2012
Great news, I do hope this works out. It's become so common it's scary, and in younger people.



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