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Smoking marijuana could be beneficial for the elderly brain
05-10-2017, 06:12 PM #1
Octo Mother Superior
Posts:43,357 Threads:1,482 Joined:Feb 2011
Senior mice treated with THC improved on learning and memory tests

Quote:Researchers led by Andreas Zimmer of the University of Bonn in Germany gave low doses of delta 9-tetrahydrocannabinol, or THC, marijuana’s main active ingredient, to young, mature and aged mice. As expected, young mice treated with THC performed slightly worse on behavioral tests of memory and learning. For example, after THC young mice took longer to learn where a safe platform was hidden in a water maze, and they had a harder time recognizing another mouse to which they had previously been exposed. Without the drug, mature and aged mice performed worse on the tests than young ones did. But after receiving THC the elderly animals’ performances improved to the point that they resembled those of young, untreated mice. “The effects were very robust, very profound,” Zimmer says.

When the researchers examined the brains of the treated, elderly mice for an explanation, they noticed neurons in the hippocampus—a brain area critical for learning and memory—had sprouted more synaptic spines, the points of contact for communication between neurons. Even more striking, the gene expression pattern in the hippocampi of THC-treated aged mice was radically different from that of untreated elderly mice. “That is something we absolutely did not expect: the old animals [that received] THC looked most similar to the young, untreated control mice,” Zimmer says.

https://www.scientificamerican.com/artic...rly-brain/

İmage
05-10-2017, 07:00 PM #2
UniqueStranger Art in my heart
Posts:15,179 Threads:429 Joined:Jun 2012
I was listening to the radio's scientist guest speaker and he is studying THC levels and driving ability. He did say that there is marked impairment with driving after smoking MJ, but the people who phoned in shared many interesting experiences, such as feeling more aware of their surroundings, more in tune, feeling as if they are driving better because they are more relaxed (even though they were driving slower - which is a good thing IMO). But, another study did warn that MJ does affect the cardiovascular system and makes the heart race, so they targeted older men as having more risk of a heart attack (I guess women too who may have issues).

So, I wish they'd quit doing these MJ studies on mice/rats and only perform them on humans because you can't talk to a rodent to ascertain if the various types of communication lines are actually working at their best.
05-10-2017, 07:03 PM #3
Meh Member
Posts:464 Threads:18 Joined:Apr 2017
I agree, and rodents cant drive a clutch. chuckle.gif
05-10-2017, 07:05 PM #4
UniqueStranger Art in my heart
Posts:15,179 Threads:429 Joined:Jun 2012
(05-10-2017, 07:03 PM)Meh Wrote:  I agree, and rodents cant drive a clutch.  chuckle.gif

chuckle.gif
05-10-2017, 07:07 PM #5
Octo Mother Superior
Posts:43,357 Threads:1,482 Joined:Feb 2011
(05-10-2017, 07:00 PM)UniqueStranger Wrote:  I was listening to the radio's scientist guest speaker and he is studying THC levels and driving ability. He did say that there is marked impairment with driving after smoking MJ, but the people who phoned in shared many interesting experiences, such as feeling more aware of their surroundings, more in tune, feeling as if they are driving better because they are more relaxed (even though they were driving slower - which is a good thing IMO). But, another study did warn that MJ does affect the cardiovascular system and makes the heart race, so they targeted older men as having more risk of a heart attack (I guess women too who may have issues).

So, I wish they'd quit doing these MJ studies on mice/rats and only perform them on humans because you can't talk to a rodent to ascertain if the various types of communication lines are actually working at their best.

They are testing on old ppl next

Quote:If this data holds up in humans…it may suggest that [THC] isn’t likely to have a negative impact if you’re using the right dose. Now the challenge is thrown down to clinical researchers to study that in people,” Ware says.

Zimmer and his colleagues plan to do just that. They have secured funding from the German government, and after clearing regulatory hurdles they will begin testing the effects of THC in elderly adults with mild cognitive impairments.
05-10-2017, 07:14 PM #6
UniqueStranger Art in my heart
Posts:15,179 Threads:429 Joined:Jun 2012
(05-10-2017, 07:07 PM)Octo Wrote:  
(05-10-2017, 07:00 PM)UniqueStranger Wrote:  I was listening to the radio's scientist guest speaker and he is studying THC levels and driving ability. He did say that there is marked impairment with driving after smoking MJ, but the people who phoned in shared many interesting experiences, such as feeling more aware of their surroundings, more in tune, feeling as if they are driving better because they are more relaxed (even though they were driving slower - which is a good thing IMO). But, another study did warn that MJ does affect the cardiovascular system and makes the heart race, so they targeted older men as having more risk of a heart attack (I guess women too who may have issues).

So, I wish they'd quit doing these MJ studies on mice/rats and only perform them on humans because you can't talk to a rodent to ascertain if the various types of communication lines are actually working at their best.

They are testing on old ppl next

Quote:If this data holds up in humans…it may suggest that [THC] isn’t likely to have a negative impact if you’re using the right dose. Now the challenge is thrown down to clinical researchers to study that in people,” Ware says.

Zimmer and his colleagues plan to do just that. They have secured funding from the German government, and after clearing regulatory hurdles they will begin testing the effects of THC in elderly adults with mild cognitive impairments.

The scientist also said they are still working on what the "right" dose is for driving unimpaired...so far, you just have to wait 2 hours after toking then you are supposedly OK but he did not go into potency + dosage, although I didn't hear all the interview, but he did mention something about being over the number 9 __? dosage but again, nothing about the person's weight, age, etc. dunno.gif

All he kept saying was that any ingestion and driving ability was impaired for everyone. I can see this will be easy to fight in court for the next few years.
05-10-2017, 07:39 PM #7
Accidental Stoner Member
Posts:9,036 Threads:74 Joined:Feb 2011
Hahahahaha - yeah, don't listen to what ordinary tokers
have had to say about it for 12 000 years...

chuckle.gif

If only the pétit bourgeoisie and the political class understood
the level of political debate among herb smokers of the world...
- waaay over their heads.

Mbwahhahaahhhahh. :D
05-10-2017, 08:24 PM #8
Kreeper Griobhtha
Posts:10,847 Threads:655 Joined:Feb 2011
(05-10-2017, 07:39 PM)Accidental Stoner Wrote:  Hahahahaha - yeah, don't listen to what ordinary tokers
have had to say about it for 12 000 years...

chuckle.gif

If only the pétit bourgeoisie and the political class understood
the level of political debate among herb smokers of the world...
- waaay over their heads.

Mbwahhahaahhhahh. :D

The political class gets it. They also get how much it is worth to keep it illegal.

Politicians hide themselves away
They only started the war
Why should they go out to fight?
They leave that role to poor
05-10-2017, 08:33 PM #9
Octo Mother Superior
Posts:43,357 Threads:1,482 Joined:Feb 2011
Senior citizens are apparently not giving two fvcks about the law anymore.

The article says:
Quote:But although young people make up the largest group of cannabis users, their rate of use has remained relatively stable over the past decade even as the drug has become increasingly available. Meanwhile, use among seniors has skyrocketed as the drug’s stigma has faded. A March study showed that in people aged 50 to 64, marijuana use increased nearly 60 percent between 2006 and 2013. And among adults over 65, the drug’s use jumped by 250 percent.
05-10-2017, 08:38 PM #10
JayRodney ⓐⓛⓘⓔⓝ
Posts:31,572 Threads:1,443 Joined:Feb 2011
(05-10-2017, 08:24 PM)Kreeper Wrote:  
(05-10-2017, 07:39 PM)Accidental Stoner Wrote:  Hahahahaha - yeah, don't listen to what ordinary tokers
have had to say about it for 12 000 years...

chuckle.gif

If only the pétit bourgeoisie and the political class understood
the level of political debate among herb smokers of the world...
- waaay over their heads.

Mbwahhahaahhhahh. :D

The political class gets it. They also get how much it is worth to keep it illegal.

It's a money making cow for a select few, as where when legal, schools and States reap the benefits. They love that all for me none for you stuff, makes 'em feel less dead.

wonder.gif
05-10-2017, 09:12 PM #11
DaJavoo If looks could kilt
Posts:1,865 Threads:45 Joined:Mar 2011
(05-10-2017, 08:33 PM)Octo Wrote:  Senior citizens are apparently not giving two fvcks about the law anymore.

The article says:
Quote:But although young people make up the largest group of cannabis users, their rate of use has remained relatively stable over the past decade even as the drug has become increasingly available. Meanwhile, use among seniors has skyrocketed as the drug’s stigma has faded. A March study showed that in people aged 50 to 64, marijuana use increased nearly 60 percent between 2006 and 2013. And among adults over 65, the drug’s use jumped by 250 percent.

Well, considering that age group and beyond were considered part of the 'hippie' generation and is basically retired and doesn't have to worry about peeing in cups, they are just falling back into their natural ways and means.

I'm sure they are finding the pot available today  is waaay better than what they toked back in the 60's.  

İmage
05-10-2017, 09:17 PM #12
UniqueStranger Art in my heart
Posts:15,179 Threads:429 Joined:Jun 2012
(05-10-2017, 09:12 PM)DaJavoo Wrote:  
(05-10-2017, 08:33 PM)Octo Wrote:  Senior citizens are apparently not giving two fvcks about the law anymore.

The article says:
Quote:But although young people make up the largest group of cannabis users, their rate of use has remained relatively stable over the past decade even as the drug has become increasingly available. Meanwhile, use among seniors has skyrocketed as the drug’s stigma has faded. A March study showed that in people aged 50 to 64, marijuana use increased nearly 60 percent between 2006 and 2013. And among adults over 65, the drug’s use jumped by 250 percent.

Well, considering that age group and beyond were considered part of the 'hippie' generation and is basically retired and doesn't have to worry about peeing in cups, they are just falling back into their natural ways and means.

I'm sure they are finding the pot available today  is waaay better than what they toked back in the 60's.  

İmage

I heard THC stays in the urine for 30 days and that may pose a problem for Canadian Snow Birds that want to cross the border into the U.S. There are going to be major problems here.

I prefer the pot back in the '60s, the stuff today is harsh and too high in THC for my liking. But now I'll be able to grow my own plants and choose the best strain for me.
05-10-2017, 09:40 PM #13
Adde Member
Posts:594 Threads:47 Joined:Apr 2012
I never thought of that, I know that THC can stay in the body over 30 days with frequent use. They could be charged with DUI coming from Canada. I can only do it once or twice a month due to random tests. gaah.gif
My mom is the stoner. chuckle.gif I envy her.
05-11-2017, 10:13 AM #14
Mars Member
Posts:468 Threads:22 Joined:Aug 2013
Same here, I can only do it a couple times a month. gaah.gif What a bunch of shït, and compromised happiness and enlightenment traded for worthless fiat paper money so I can feed myself.
Anonymous Kritter Show this Post
05-11-2017, 11:09 AM #15
Anonymous Kritter Incognito Anonymous
 
Oregon has a bill that would prevent drug tests for THC as it's legal for recreational use. If it passes the rest of the States that are legal for recreational use are expected to follow.



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